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pentobarbital will lessen the extent or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.lumefantrine will minimize the level or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.apalutamide will decrease the extent or impact of diazepam by impacting hepat